PHARMACOLOGIC MANAGEMENT OF BONE-RELATED COMPLICATIONS AND BONE METASTASES IN POSTMENOPAUSAL WOMEN WITH HORMONE RECEPTOR-POSITIVE BREAST CANCER

Pharmacologic management of bone-related complications and bone metastases in postmenopausal women with hormone receptor-positive breast cancer

Denise A Yardley1,2 1Sarah Cannon Research Institute, Nashville, TN, USA; 2Tennessee Oncology, Nashville, TN, USA Abstract: There is a high risk for bone loss and skeletal-related events, including bone metastases, in postmenopausal women with hormone receptor-positive breast cancer.Both the disease itself and its therapeutic treatments can negativ

read more

SARS-CoV-2 Vaccination Responses in Anti-CD20-Treated Progressive Multiple Sclerosis Patients Show Immunosenescence in Antigen-Specific B and T Cells

Clinical, pathological, and imaging evidence in multiple sclerosis (MS) shows that inflammation starts early and progresses with age.B cells play a central role in this process, contributing to cytokine production, defective regulatory functions, and abnormal immunoglobulin production, even in the central nervous system.Anti-CD20 (aCD20) therapies,

read more

The Culture of Patriotism as a Scientific Concept in Modern Social Philosophy: Actualization of the Problem Field

In the conditions of modern social challenges there is an actualization of Flashlights humanitarian research aimed at studying the problems of patriotism.At present, the comprehension of the nature of patriotism, factors of its development in society, conditions of deformation of patriotic consciousness acquires a high degree of relevance.Understan

read more